CHICAGO – November 11, 2004 – As the scientific community is seeking alternatives to antibiotic treatment, periodontal researchers found
that photodynamic
“Although this study is still in its early phase, with the recent number of reports about bacterial strains becoming resistant to frequent doses
of antibiotics, PDT could be an alternative to conventional periodontal therapeutic methods,” said
PDT involves two stages. In the first stage, a light-sensitive drug is applied. The second stage involves shining a light or laser directly on the area treated with the drug. When the light is combined with the drug, phototoxic reactions are induced which destroy bacterial cells. PDT was first approved by the Food and Drug Administration in 1999 to treat pre-cancerous skin lesions of the face or scalp.
In this study, researchers investigated anaerobic bacterial strains (bacteria that can only survive and grow in the absence of molecular oxygen) and facultative anaerobic bacteria (bacteria that can survive without oxygen).
“The photosensitizers we investigated were able to completely suppress the anaerobic key pathogens leading to periodontal diseases; however,
facultative anaerobic bacteria tested responded to a lesser extent to PDT,” said
To specifically address the periodontal pockets in the body, the test tube results are presently being verified in several animal and human experiments.
A referral to a periodontist in your area and
For more information, contact the AAP Public Affairs Department at
EDITOR'S NOTE: Representatives of the media may contact the AAP Public Affairs Department to receive a copy of the study "Killing Periodontopathogenic Bacteria by Photodynamic Therapy." Abstracts of Journal of Periodontology articles are available to the public online. Full-text of studies may be accessed by AAP members and Journal subscribers or purchased online for $20.
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