Researchers found that when patients with Type 2 diabetes and periodontal disease receive periodontal therapy, their levels of oxidative stress are reduced to those of nondiabetic patients...

Periodontal Therapy Helps Patients With Type 2 Diabetes

Researchers find oxidative stress levels reduced to those of nondiabetic patients

CHICAGO—October 31, 2006—When patients with Type 2 diabetes and periodontal disease receive periodontal therapy, they often experience a reduction in their levels of oxidative stress, a condition in which antioxidant levels are lower than normal. Patients' stress levels after periodontal therapy were similar to those of nondiabetic patients, according to a new study that appeared in the November issue of the Journal of Periodontology (JOP). Study Abstract *

Researchers from Kyushu Dental College in Kitakyushu, Japan investigated the impact of periodontal therapy on patients with Type 2 diabetes, as compared to nondiabetic patients. They found that periodontal therapy decreased lipid peroxide (LPO), an oxidative stress index, in diabetic patients.

“Our research emphasized one of the benefits of having periodontal therapy for patients with diabetes,” said Dr. Kazuo Sonoki, M.D. PhD at Kyushu Dental College, one of the study authors. “However, this was just a preliminary study and more research should be conducted to evaluate how periodontal disease affects both people with and without diabetes.”

It has been found that diabetes and periodontal disease can lead to atherosclerosis, which occurs when deposits of fatty substances, cholesterol, and other substances build up in the inner lining of an artery. This buildup is called plaque. It has been thought that oxidative stress is linked to heart disease because oxidation of LDL (low-density lipoprotein) in the endothelium is a precursor to plaque formation. Recently, oxidative stress has emerged as an important factor for atherosclerosis in patients with diabetes.

“We hear every day about how more and more people are being diagnosed with diabetes,” said Preston D. Miller, DDS and AAP president. “This research confirms that patients with diabetes should be especially conscious of their periodontal health. While more research needs to be done to evaluate the relationship between periodontal disease and diabetes, we do know that treating periodontal diseases can save teeth, and can promote overall health.”

A referral to a periodontist in your area and free brochure samples including one titled Diabetes & Periodontal Diseases are available by calling 800-FLOSS-EM or visiting the AAP's Web site at www.perio.org.

About the AAP

The American Academy of Periodontology is an 8,000-member association of dental professionals specializing in the prevention, diagnosis and treatment of diseases affecting the gums and supporting structures of the teeth and in the placement and maintenance of dental implants. Periodontics is one of nine dental specialties recognized by the American Dental Association.

For more information, contact the AAP Public Affairs Department at 312/573-3242.

* EDITOR'S NOTE: Representatives of the media may contact the AAP Public Affairs Department to receive a copy of the articles Decreased lipid peroxidation following periodontal therapy in type 2 diabetic patients. Abstracts of Journal of Periodontology articles are available to the public online. Full-text of studies may be accessed by AAP members and Journal subscribers or purchased online for $20.

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