Meta Analysis on Bone Replacement Grafts for Periodontal Defects
Reynolds MA, Aichelmann-Reidy ME, Branch-Mays GL, Gunsolley JC. The efficacy of bone replacement grafts in the treatment of periodontal osseous defects. A systematic review. Ann Periodontol. 2003 Dec;8(1):227-65. Review.
Meta Analysis on Guided Tissue Regeneration of Periodontal Defects
Gaurell L, Gottlow J, Zybutz M, Persson R. Treatment of intrabony defects by different surgical procedures. A literature review. J Periodontol. 1998 Mar;69(3):303-13.
Murphy KG, Gunsolley JC. Guided tissue regeneration for the treatment of periodontal intrabony and furcation defects. A systematic review. Ann Periodontol. 2003 Dec;8(1):266-302. Review.
Needleman I, Worthington HV, Giedrys-Leeper E, Tucker R. Guided tissue regeneration for periodontal infra-bony defects. Cochrane Database of Systematic Reviews 2006, Issue 2. Art. No.: CD001724. DOI: 10.1002/14651858.CD001724.pub2.
Machtei EE. The effect of membrane exposure on the outcome of regenerative procedures in humans: a meta-analysis. J Periodontol. 2001 Apr;72(4):512-6.
Meta-analysis of Biomimetic agents
Kalpidis CD, Ruben MP. Treatment of intrabony periodontal defects with enamel matrix derivative: a literature review. J Periodontol. 2002 Nov;73(11):1360-76. Review.
Venezia E, Goldstein M, Boyan BD, Schwartz Z. The use of enamel matrix derivative in the treatment of periodontal defects: a literature review and meta-analysis. Crit Rev Oral Biol Med. 2004 Nov 1;15(6):382-402. Review.
Tu YK, Woolston A, Faggion CM Jr. Do bone grafts or barrier membranes provide additional treatment effects for infrabony lesions treated with enamel matrix derivatives? A network meta-analysis of randomized-controlled trials. J Clin Periodontol. 2010 Jan;37(1):59-79.
Esposito M, Grusovin MG, Papanikolaou N, Coulthard P, Worthington HV. Enamel matrix derivative (Emdogain®) for periodontal tissue regeneration in intrabony defects. Cochrane Database of Systematic Reviews 2009, Issue 4. Art. No.: CD003875. DOI: 10.1002/14651858.CD003875.pub3.
Tu, Y.-K., Needleman, I., Chambrone, L., Lu, H.-K. and Faggion, C. M. (2012), A bayesian network meta-analysis on comparisons of enamel matrix derivatives, guided tissue regeneration and their combination therapies. Journal of Clinical Periodontology, 39: 303–314. doi: 10.1111/j.1600-051X.2011.01844.x
Meta Analysis on Periodontal Regeneration in Furcation
Kinaia BM, Steiger J, Neely AL, Shah M, Bhola M. Treatment of Class II molar furcation involvement: meta-analyses of reentry results. J Periodontol. 2011 Mar;82(3):413-28.
Murphy KG, Gunsolley JC. Guided tissue regeneration for the treatment of periodontal intrabony and furcation defects. A systematic review. Ann Periodontol. 2003 Dec;8(1):266-302. Review.
Randomized Controlled Trial on Periodontal Regeneration
1. Guided Tissue Regeneration of Periodontal Defects and Furcations
Eickholz P, Pretzl B, Holle R, Kim TS. Long-term results of guided tissue regeneration therapy with non-resorbable and bioabsorbable barriers. III. Class II furcations after 10 years. J Periodontol. 2006 Jan;77(1):88-94.
Nygaard-Østby P, Bakke V, Nesdal O, Nilssen HK, Susin C, Wikesjö UM. Periodontal healing following reconstructive surgery: effect of guided tissue regeneration using a bioresorbable barrier device when combined with autogenous bone grafting. A randomized controlled clinical trial. J Clin Periodontol. 2008 Jan;35(1):37-43.
Pretzl B, Kim TS, Steinbrenner H, Dörfer C, Himmer K, Eickholz P. Guided tissue regeneration with bioabsorbable barriers III 10-year results in infrabony defects. J Clin Periodontol. 2009 Apr;36(4):349-56. Epub 2008 Mar 11.
Nickles K, Ratka-Krüger P, Neukranz E, Raetzke P, Eickholz P. Open flap debridement and guided tissue regeneration after 10 years in infrabony defects. J Clin Periodontol. 2009 Nov;36(11):976-83. Epub 2009 Oct 6.
Stavropoulos A, Karring T. Guided tissue regeneration combined with a deproteinized bovine bone mineral (Bio-Oss) in the treatment of intrabony periodontal defects: 6-year results from a randomized-controlled clinical trial. J Clin Periodontol. 2010 Feb;37(2):200-10.
Cortellini P, Stalpers G, Mollo A, Tonetti MS: Periodontal regeneration versusextraction and prosthetic replacement of teeth severely compromised by attachment loss to the apex: 5-year results of an ongoing randomized clinical trial. J Clin Periodontol 2011; 38: 915–924. doi: 10.1111/j.1600-051X.2011.01768.x
2. Use of Biomimetic agents
Yukna RA, Krauser JT, Callan DP, Evans GH, Cruz R, Martin M. Multi-center clinical comparison of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) and ABM in human periodontal osseous defects. 6-month results. J Periodontol. 2000 Nov;71(11):1671-9. Erratum in: J Periodontol 2001 Apr;72(4):570
Nevins M, Giannobile WV, McGuire MK, Kao RT, Mellonig JT, Hinrichs JE, McAllister BS, Murphy KS, McClain PK, Nevins ML, Paquette DW, Han TJ, Reddy MS, Lavin PT, Genco RJ, Lynch SE. Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial. J Periodontol. 2005 Dec;76(12):2205-15.
Yilmaz S, Cakar G, Yildirim B, Sculean A. Healing of two and three wall intrabony periodontal defects following treatment with an enamel matrix derivative combined with autogenous bone. J Clin Periodontol. 2010 Jun;37(6):544-50.
Meyle J, Hoffmann T, Topoll H, Heinz B, Al-Machot E, Jervøe-Storm PM, Meiss C, Eickholz P, Jepsen S. A multi-centre randomized controlled clinical trial on the treatment of intra-bony defects with enamel matrix derivatives/synthetic bone graft or enamel matrix derivatives alone: results after 12 months. J Clin Periodontol. 2011 Jul;38(7):652-60. doi: 10.1111/j.1600-051X.2011.01726.x. Epub 2011 May 12
Röllke L, Schacher B, Wohlfeil M, Kim TS, Kaltschmitt J, Krieger J, Krigar DM, Reitmeir P, Eickholz P. Regenerative therapy of infrabony defects with and without postsurgical doxycycline. A randomized placebo-controlled trial. J Clin Periodontol 2012; 39: 448–456 doi: 10.1111/j.1600-051X.2012.01861.x.
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